More than $585 Billion in New U.S. Investment Since 2025
America leads the world in healthcare innovation and access, and a strong medical infrastructure is essential to maintain this standing for our national security.
The world’s pharmaceutical companies are stepping up their investments in America.
We Work For Health’s tracking tool, the U.S. Biopharma Investment Watch, is documenting these developments and providing visibility into the sector's robust expansion and critical role in securing America's position as the global leader in health care innovation. Since January 2025, companies have committed to investing more than $585 billion to bolster U.S. research and development, expand manufacturing, and create jobs across the country.
Investment in America
These investments bring cutting edge treatments closer to the patients who need them while bolstering America’s position as a world leader in healthcare access and innovation. The positive impact of these investments reaches deep into U.S. communities, powering high-skill positions for scientists and engineers, construction and production support roles, and millions of jobs for the communities surrounding the facilities. This builds upon more than 4.9 million total U.S. jobs and $71.6 billion in vendor spending in states along with $2.6B in wages paid to the American construction workforce.
The tracker reflects the sector’s commitment to preserving American leadership in the life sciences, as China continues a coordinated campaign to overtake it.
1,488%
increase in announced U.S. facility investments in 2025 vs 2024
Tens of Thousands
of new construction jobs across America
Faster delivery
of breakthrough medicines to U.S. patients
It’s essential to have the right policies in place that encourage continued investment to secure America’s future as the global leader in life sciences.
U.S. Biopharma Investment Watch
Legend:
Announcement date
Company
Investment amount
Investment location(s)
May 12, 2025
Roche
$700 million
Holly Springs-NC
The first East Coast manufacturing site for Genentech (Roche’s U.S. subsidiary) is a fill-finish biologics plant that will produce metabolic medicines, including next-gen obesity treatments, to support growing demand.
The project is part of Roche’s $50B U.S. initiative and will create more than 400 local full-time jobs when operational (2029) and about 1,500 construction jobs during development.
May 12, 2025
Roche
$550 million
Indianapolis-IN
Expanding its campus into a major hub for manufacturing continuous glucose monitoring (CGM) systems for diabetes management and adding a new diagnostics production facility.
The expansion is expected to create “hundreds” of skilled manufacturing jobs and thousands of construction jobs in Indiana.
May 7, 2025
Gilead
$4 billion
Unspecified location
Gilead announced an $11 billion U.S. investment initiative (supplementing $21 billion already planned through 2030) to expand its domestic manufacturing and R&D footprint. About $4 billion will go into capital projects: three new facilities and three upgraded sites to boost U.S. production and lab capacity.
Gilead estimated this phase will create about 800 new U.S. jobs and over 2,200 indirect jobs by 2028.
Apr 25, 2025
AbbVie
$10 billion
Unspecified location
Committed to a $10 billion U.S. expansion over the next decade to grow its manufacturing footprint, including funding four new U.S. production facilities dedicated to active pharmaceutical ingredients, finished drug products, peptide therapeutics, and medical devices.
Apr 24, 2025
Thermo Fisher Scientific
$2 billion
Unspecified location
Pledged an additional $2 billion over four years to strengthen its U.S. innovation and manufacturing infrastructure. The investment includes $1.5 billion to expand U.S. manufacturing operations and $500 million for R&D of “high-impact” innovation.
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Methodology
All investments data comes from publicly available resources. Investments may span across multiple states and, therefore, are reflected on each state page. Investment locations will be updated once specified.
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Jobs data source: WWFH “in the states” page
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Labor hours data source: PILMA jobs report page