
More than $582 Billion in New U.S. Investment Since 2025
America leads the world in healthcare innovation and access, and a strong medical infrastructure is essential to maintain this standing for our national security.
The world’s pharmaceutical companies are stepping up their investments in America.
We Work For Health’s tracking tool, the U.S. Biopharma Investment Watch, is documenting these developments and providing visibility into the sector's robust expansion and critical role in securing America's position as the global leader in health care innovation. Since January 2025, companies have committed to investing more than $582 billion to bolster U.S. research and development, expand manufacturing, and create jobs across the country.
Investment in America
These investments bring cutting edge treatments closer to the patients who need them while bolstering America’s position as a world leader in healthcare access and innovation. The positive impact of these investments reaches deep into U.S. communities, powering high-skill positions for scientists and engineers, construction and production support roles, and millions of jobs for the communities surrounding the facilities. This builds upon more than 4.9 million total U.S. jobs and $71.6 billion in vendor spending in states along with $2.6B in wages paid to the American construction workforce.
The tracker reflects the sector’s commitment to preserving American leadership in the life sciences, as China continues a coordinated campaign to overtake it.
1,488%
increase in announced U.S. facility investments in 2025 vs 2024
Tens of Thousands
of new construction jobs across America
Faster delivery
of breakthrough medicines to U.S. patients
It’s essential to have the right policies in place that encourage continued investment to secure America’s future as the global leader in life sciences.

U.S. Biopharma Investment Watch
Legend:
Announcement date
Company
Investment amount
Investment location(s)
May 7, 2025
Gilead
$4 billion
Unspecified location
Gilead announced an $11 billion U.S. investment initiative (supplementing $21 billion already planned through 2030) to expand its domestic manufacturing and R&D footprint. About $4 billion will go into capital projects: three new facilities and three upgraded sites to boost U.S. production and lab capacity.
Gilead estimated this phase will create about 800 new U.S. jobs and over 2,200 indirect jobs by 2028.
Apr 25, 2025
AbbVie
$10 billion
Unspecified location
Committed to a $10 billion U.S. expansion over the next decade to grow its manufacturing footprint, including funding four new U.S. production facilities dedicated to active pharmaceutical ingredients, finished drug products, peptide therapeutics, and medical devices.
Apr 24, 2025
Thermo Fisher Scientific
$2 billion
Unspecified location
Pledged an additional $2 billion over four years to strengthen its U.S. innovation and manufacturing infrastructure. The investment includes $1.5 billion to expand U.S. manufacturing operations and $500 million for R&D of “high-impact” innovation.
Apr 22, 2025
Roche
$50 billion
AZ, CA, IN, KY, NJ, OR
Launched a sweeping plan to invest around $50 billion across its U.S. pharmaceutical and diagnostics operations over five years.
Roche will build multiple new facilities – including a gene therapy production plant in Pennsylvania, a new continuous glucose monitor device factory in Indiana, an AI-focused R&D center in Massachusetts and a 900,000 sq ft biologics facility for next-gen weight-loss drugs (location TBD).
It is also expanding and upgrading existing manufacturing and distribution sites in Kentucky, Indiana, New Jersey, Oregon, and California, and enlarging R&D centers in Arizona, Indiana, and California.
This effort will create over 12,000 U.S. jobs (1,000 directly at Roche and ~11,000 via supporting industries) and ensure Roche produces more medicines in the U.S. than it imports
4 new facilities and 3 existing pharma and diagnostic R&D centers; includes diagnostics investments (will expand its diagnostic manufacturing sites in Kentucky, Indiana, New Jersey, Oregon and California). +4,500 additional jobs through multiplier
Apr 10, 2025
Novartis
$23 billion
Indianapolis-IN, San Diego-CA, Millburn-NJ, Carlsbad-CA
Announced a five-year plan to spend $23 billion to build and expand 10 drug production and R&D facilities in the United States. These include constructing six new manufacturing plants and a new R&D hub in the San Diego area. Four of the plant locations are still to be decided, but two will be built in Florida and Texas to produce certain cancer therapies.
The company will also expand 3 manufacturing facilities in Indianapolis, IN, Millburn, NJ, and Carlsbad, CA.
These investments are expected to create more than 1,000 jobs for skilled workers like engineers and scientists as well as another 4,000 support staff and construction jobs and will enable the company to manufacture 100% of its key medicines in the U.S.
Mar 21, 2025
Johnson & Johnson
$55 billion
Wilson-NC, Unspecified location
Unveiled a plan to invest over $55 billion in U.S. manufacturing, R&D, and technology by 2029 – a 25% increase in domestic investment that includes building four new advanced manufacturing facilities in the United States.
J&J broke ground on the first facility on March 21in Wilson, North Carolina which will employ over 500 people and support ~5,000 construction jobs. The new, state-of-the art biologics manufacturing facility will significantly expand the company’s capacity to manufacture next-generation medicines for people living with cancer, immune-mediated and neurological diseases around the world.
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Methodology
All investments data comes from publicly available resources. Investments may span across multiple states and, therefore, are reflected on each state page. Investment locations will be updated once specified.
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Jobs data source: WWFH “in the states” page
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Labor hours data source: PILMA jobs report page