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$268 Billion in U.S. Life Science Investment in 2025

America leads the world in healthcare innovation and access, and a strong medical infrastructure is essential to maintain this standing for our national security.

This year, the life sciences sector has delivered.

We Work For Health is tracking every new U.S. biopharma facility announcement and news report, revealing more than $268 billion invested to drive new R&D, expand manufacturing and create jobs nationwide.

Investment in America

These investments bring cutting edge treatments closer to the patients who need them while bolstering America’s position as a world leader in healthcare access and innovation. The positive impact of these investments reaches deep into U.S. communities, with millions of high-skill positions for scientists and engineers, alongside tens of thousands of construction and support roles and millions of jobs for the communities surrounding these cutting edge faciltiies. This includes more than 4.9 million total U.S. jobs and $71.6 billion in vendor spending in states along with $2.6B in wages paid to the American construction workforce.

766%

increase in facility investment announcements versus 2024

10K+

new construction jobs across America

The biopharmaceutical industry’s investments reflect a commitment to ensuring the U.S. remains a leader in the life sciences, but China continues a coordinated campaign to dominate the life sciences, jeopardizing America’s momentum.

It’s essential to 
have the right policies in place that encourage continued investment to secure America’s future as the global leader in life sciences.

Faster delivery

of breakthrough medicines to patients

U.S. Life Sciences Investment Tracker:

June 28, 2025

Hikma

$1 billion

Cherry Hill-NJ, Dayton-NJ, Cleveland-OH, Columbus-OH

Capability expansion for generic medicine manufacturing and R&D.

June 16, 2025

Sanner

Unspecified

Greensboro-NC

Germany-based company to build a 60,500-square-foot manufacturing facility dedicated to producing critical injection-molded components for medical devices and pharmaceutical packaging, as well as desiccant solutions

June 12, 2025

UCB

$2 billion

Unspecified location

Announced plans to build a new biologics manufacturing facility as part of long-term growth strategy. The project is expected to have about a $5 billion economic impact, creating about 300 permanent high-skill jobs and over 500 construction jobs.

May 18, 2025

Ratio Therapeutics

Unspecified

Salt Lake City-UT

New research and manufacturing facility, supporting vertical integration of Ratio's current and future pipeline of next-generation radiopharmaceuticals.

May 14, 2025

Sanofi

$20 billion

Unspecified location

Substantially increasing spending on U.S. R&D. Sanofi also announced plans to expand U.S.  manufacturing capacity, both through direct investments in Sanofi sites, as well as through partnerships with other domestic manufacturers, to help ensure the production of medicines in the U.S.

May 12, 2025

Roche

$550 million

Indianapolis-IN

Expanding its campus into a major hub for manufacturing continuous glucose monitoring (CGM) systems for diabetes management and adding a new diagnostics production facility. 


The expansion is expected to create “hundreds” of skilled manufacturing jobs and thousands of construction jobs in Indiana. 

May 12, 2025

Roche

$700 million

Holly Springs-NC

The first East Coast manufacturing site for Genentech (Roche’s U.S. subsidiary) is a fill-finish biologics plant that will produce metabolic medicines, including next-gen obesity treatments, to support growing demand.


The project is part of Roche’s $50B U.S. initiative and will create more than 400 local full-time jobs when operational (2029) and about 1,500 construction jobs during development.

May 8, 2025

Takeda

$30 billion

Unspecified location

Investing in U.S. operations over the next five years to upgrade and improve U.S. manufacturing sites.

May 7, 2025

Gilead

$4 billion

Unspecified location

Gilead announced an $11 billion U.S. investment initiative (supplementing $21 billion already planned through 2030) to expand its domestic manufacturing and R&D footprint. About $4 billion will go into capital projects: three new facilities and three upgraded sites to boost U.S. production and lab capacity.


Gilead estimated this phase will create about 800 new U.S. jobs and over 2,200 indirect jobs by 2028.

May 6, 2025

BMS (Bristol Myers Squibb)

$40 billion

Unspecified location

A U.S. investment pledge across five years to expand research, technology, and manufacturing capabilities. BMS seeks to gain control over complex supply chains, ensuring its medicines are made closer to the patients who need them.

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