December 9, 2025
Eli Lilly
Huntsville-AL
A new, next-generation active pharmaceutical ingredient (API) facility that will support the production of small molecule synthetic and peptide medicines, including an oral GLP-1. The project will bring “450 high-value jobs” to the area, including engineers, scientists, operations personnel and lab technicians, and 3,000 construction jobs.
Part of a larger, previously announced $27 billion company investment.
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October 29, 2025
Eli Lilly
Carolina-PR
Expansion and modernization of the Lilly del Caribe manufacturing site to support the company's growing portfolio of oral solid medicines in cardiometabolic health, neuroscience, oncology and immunology. The project will generate an estimated 1,000 construction jobs and 100 additional high-tech manufacturing positions.
Part of a larger, previously announced $27 billion company investment.
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November 19, 2025
Novartis
Durham-NC, Morrisville-NC
A new site in Durham featuring two facilities dedicated to manufacturing biologics and sterile packaging. Also an expansion of an existing Durham facility with the added capability to support sterile filling of biologics into syringes and vials.
A new site in Morrisville with one facility for the production of solid dosage tablets and capsules, including packaging.
Part of a larger, previously announced $23 billion company investment.
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November 21, 2025
AstraZeneca
Frederick-MD, Gaithersburg-MD
Expansion of the company’s flagship biologics manufacturing facility in Frederick and the construction of a new state-of-the-art facility in Gaithersburg for the development of innovative molecules to be used in clinical trials.
The investment will support 2,600 jobs across the two sites, including the retention of local jobs, construction activity, and the creation of 300 highly skilled jobs.
Part of a larger, previously announced $50 billion company investment.
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